| MERGERS & ACQUISITIONS |
| Acquiring Company |
Target |
Deal Summary |
| Agilent Technologies |
Multiplicom, Belgiumbased molecular diagnostics firm spun off from Univ. of Antwerp in 2011 |
- Price: €68 million ($70.6 million) in cash
- AT to offer jobs to all 90 M employees
- Lure is M's BRCA Tumor MASTR Plus Dx test, first ovarian cancer companion test to get CE-IVD designation in Europe
|
| Menarini-Silicon Biosystems |
Janssen Diagnostics |
- MSB acquires JD's Cellsearch circulating tumor cell system for monitoring breast, prostate and colorectal cancers
- Cellsearch is only breast cancer monitoring system approved by China FDA
|
| Abbott Laboratories |
St. Jude Medical |
- European Commission OKs on antitrust grounds provided that: i. SJ divests Angio-Seal and Femoseal vascular closure assets; and ii. A divests Vado steerable sheath
- All latter assets already slated for sale to Japanese firm Terumo for $1 billion
|
| Takara Bio USA Holdings |
Rubicon Genomics |
- Helps T fortify position in pre-analytical genetic sample preparation and expand into in vitro fertilization
|
| Grifols |
Hologic, Inc.'s blood screening assets |
- Price: $1.85 billion cash gross proceeds
- G and H were partners in blood screening business with H doing R&D and manufacturing and G concentrating on commercialization
|
| Abbott Laboratories |
Alere |
- Abbott sues to get out of $5.8 billion acquisition deal inked in Feb. (See LIR, Dec. 2016)
|
| DNA Diagnostics Center |
Identigene, subsidiary of Sorenson Genomics |
- US/UK-based DDC acquires first company to sell in-home DNA paternity test collection kits in US mass retail stores including Rite Aid, CVS and Walmart
|
| Boston Scientific |
Neovasc |
- BS acquires 15% equity stake + N's advanced biological tissue business
|
| Takara Bio USA Holdings (subsidiary of Takara Bio USA) |
Wafergen Biosystems |
- W shareholders approve merger announced in May
- Price: Aggregate cash price based on a multiple of W's 2016 calendar year revenues up— subject to $50 million cap
- T to make two separate $2.5 million deposits in Jan.
|
| STRATEGIC ALLIANCES |
| Partner 1 |
Partner 2 |
Deal Summary |
| Henry Ford Health System Pathology and Laboratory Medicine |
Beckman Coulter Inc. |
- Purpose 1: Fully automate HF Hospital lab
- Purpose 2: Modernize equipment at 12 other HF locations
|
| Roche |
Pacific Biosciences |
- R ends 2013 $75 million agreement with PacBio to develop and commercialize diagnostic single-molecule sequencing system, effective Feb. 10, 2017
|
| Agilent Genomics (the genomics arm of Agilent Technologies) |
Transcriptic (Bay Area diagnostic software firm) |
- Incorporates AG mutagenesis and cloning product lines to protocol library within T's robotic cloud laboratory
- Deal covers AG's QuikChange site-directed mutagenesis kits
|
| Novogene |
AITbiotech |
- Form NovogeneAIT Genomics Singapore, a joint venture to establish a whole-genome sequencing and bioinformatics center in Singapore
- Joint venture will also collaborate with Genome Institute of Singapore in developing use of whole-genome sequencing for cancer diagnosis
|
| Royal Phillips |
New York Medical College |
- Expansion of current partnership to develop IntelliSpace Genomics, an application that provides analysis workflows for pathologists, oncologists and researchers by integrating raw data from multiple sources
|
| Evogen |
UCB |
- Collaboration to develop EvoScore START, a diagnostic test that measures a panel of blood-based protein biomarkers to distinguish between epileptic seizures and other events
|
| Courtagen Life Sciences |
Certainty Health |
- Gives Courtagen exclusive access to CH's mobile device-based data sharing platform for neurological diseases
- Allows Courtagen to import its own neurological disease data into the platform
|
| SystemOne |
Daktari Diagnostics |
- Partnership to improve workflow and identify operational efficiencies for catheterization and electrophysiology labs at UH Cleveland Medical Center
|
| DISTRIBUTION AGREEMENTS |
| Property Owner |
Distributor |
Deal Summary |
| MDxHealth |
AceCGT Life Sciences Limited |
- Product: Prostate Cancer test
- Territory: Hong Kong Macao
|
| Dovetail Genomics LLC |
Tomy Digital Biology Co. |
- Product: Genome assembly services for researchers
|
| Illumina Netherlands |
GenDx |
- Product: Next-generation sequencing instruments and reagents used for HLA sequencing
- Territory: UK, Germany, Italy, Belgium, Netherlands, Luxembourg, Finland
- Non-exclusive reselling rights
|
| NantHealth |
Oncotest-Teva (subsidiary of Teva Pharmaceuticals) |
- Product: GPS Cancer molecular test
- Exclusive reselling rights
|
| NantHealth |
Lunatus |
- Product: GPS Cancer molecular test
- Territory: Middle East, including UAE, Kuwait, Saudi Arabia, Oman, Bahrain, Qatar, Lebanon
- Exclusive reselling rights
|
| Argos Technologies |
Bibby Scientific |
- Products: Molecular and cell biology research products, storage and cryo-storage equipment
- Territories: Europe, Middle East, Africa
|
| Kapa Biosystems (owned by Roche) |
Merck |
- Products: Extends existing distribution alliance to include Kapa's polymerase chain reaction (PCR) and quantitative real-time PCR (qPCR) enzyme products
- Territory: All markets except US, Japan and Brazil
|
| Kapa Biosystems (owned by Roche) |
MilliporeSigma |
- Products: Extends existing distribution agreement to include Kapa's polymerase chain reaction (PCR) and quantitative real-time PCR (qPCR) enzyme products
- Territory: All markets except US, Japan and Brazil
|
| Senseonics |
Roche |
- Product: Eversense, S's long-term implantable continuous glucose monitor
- Territory: Extends current distributorship agreement covering Germany, Italy and the Netherlands to all of Europe (except Scandinavia), the Middle East (except Israel) and Africa
- Exclusive sale, promotion and marketing rights
|
| LICENSES |
| Licensor |
Licensee |
Deal Summary |
| Thermo Fisher Scientific |
Singulex |
- Product: TF's BRAHMS PCT procalcitonin immunoassay
- PCT used in US to assess critically ill patients' risks of severe sepsis and septic shock and mortality risks of patients diagnosed with sepsis
- FDA recently approved use of PCT for critically ill patients before admission to the ICU (previously, the patient had to be in the ICU already)
- Non-exclusive: Thermo has also licensed PCT to Roche and Biomérieux
|
| Labcyte |
Notable Labs |
- Product: L's Echo acoustic liquid handling technology for personalizing drug therapy
- NL will use Echo in its own labs to functionally assess effects of FDA-approved drugs on live primary cancer cells from individual patients
|
| Epicentre (a subsidiary of Illumina) |
Lucigen |
- Products: Array of research products from E's AmpliScribe, CopyControl, MaxPlax and TranforMax product lines
- L to take over manufacture and sale
|
| SELLING & MARKETING AGREEMENTS |
| Property Owner |
Seller |
Deal Summary |
| Good Start Genetics |
Roche Diagnostics |
- Product: Gene Vu, GSG's screening test to identify carriers of genetic disorders
- R to sell Gene Vu along with its own Harmony prenatal fetal aneuploidy test
|
| Edico Genome |
Amazon Web Services |
- Provides for E's Dragen bioinformatics platform to be sold on new Amazon cloud-based instances
|
