MERGERS, ACQUISITIONS & ASSET SALES |
Acquiring Company |
Target(s) |
Deal Summary |
Roche |
Flatiron Health |
- Price: $1.9 billion
- Status: Expected to close in first half 2018
- Roche already 13% stakeholder in Flatiron
- Acquisition of Flatiron’s oncology technology assets boosts Roche’s personalized healthcare infrastructure
|
Qiagen |
STAT-Dx |
- Price: Up to $191 million—$147 million cash + milestone payments of up to $44 million
- Status: Expected to close in Q2 2018
- Qiagen enters multiplex infectious disease testing market by acquiring Barcelona-based developer of real-time PCR technology for molecular NGS simultaneous detection of oncology, respiratory, gastrointestinal and other infections
|
LGC |
Lucigen |
- Price: Undisclosed
- Status: Closed
- LGC acquires Wisconsin-based producer of molecular biology enzymes, reagents and kits
|
Eurofins Scientific |
Labo Van Poucke |
- Price: Undisclosed
- Status: Closed
- Eurofins gets into Belgian market by acquiring local family-owned lab with €5 million ($6.2 million) in 2017 revenues
|
Quest Diagnostics |
Mobile Medical Examination Service |
- Price: Undisclosed
- Status: Expected to close Q1 2018
- Acquiring provider of home-based health risk assessments and related services expands Quest’s position in home and mobile services
|
DiscernDx |
Applied Proteomics |
- Price: $1.85 million
- Status: Closed
- Liquidation sale in which DiscernDx acquires all assets of San Diego-based proteomics firm launched in 2007
|
Elsevier
(part of RELX Group) |
Via Oncology |
- Price: Undisclosed
- Status: Closed
- Elsevier acquires Pittsburgh-based provider of decision support and cancer care management services
|
STRATEGIC ALLIANCES, PARTNERSHIPS & COLLABORATIONS |
Partner 1 |
Partner 2 |
Deal Summary |
Thermo Fisher Scientific |
Quest Diagnostics |
- Objective: Offer Thermo Fisher’s Oncomine Dx Target Test diagnostic panel for non-small cell lung cancer
- Dynamic: Quest to perform test at its Lewisville, Texas oncology center of excellence
- Quest to also have early access to Thermo Fisher’s pipeline of novel platforms and assays to assist with development of Oncomine-branded solutions for clinical and biopharma applications
|
Roche |
Wisconsin Diagnostic Laboratories of Milwaukee |
- Strategic alliance
- WDLM named Roche Molecular Center of Excellence
|
Science Exchange |
OnRamp BioInformatics |
- Objective: Deliver bioinformatics services and tools
- Dynamic: Science Exchange to provide R&D support to OnRamp Bio for its user interface, automated analyses and genomic data management products
|
Somalogic |
Leeds Centre for Personalised Medicine and Health |
- Objective: Research capacity of protein measurements to impact patient care in different clinical areas
- Dynamic: Leverage Somalogic’s SomaScan proteomic platform to measure large numbers of proteins in blood and other patient samples
- Latest step in Somalogic’s larger strategy to develop SomaScan as clinical tool
|
Sciex |
IROA Technologies |
- Objective: Provide system for identification and quantitation of metabolites in biological samples
- Dynamic: Joint promotion of system that combines IROA’s workflow for isotopic ratio outlier analysis with Sciex’s Swath data-independent acquisition workflow on next-generation metabolomics and Triple- TOF systems
|
Medidata |
Syapse |
- Objective: Develop products to improve patient access to oncology clinical trials
- Dynamic: Partners to initially focus on creating products to help trial sponsors design eligibility criteria, identify community health systems trial sites and find patients to enroll in trials
|
Syapse |
Seoul National University Hospital + Megazone |
- Objective: Deliver precision oncology services to Asian market—S. Korea, Japan, Vietnam
- Dynamic: Seoul National University Cancer Hospital to install Syapse data-aggregation platform in its 28 centers across Korea
- Megazone, an Amazon Web Services consulting partner in Asia, to provide IT support
|
Agilent |
Science Exchange |
- Objective: Promote access to Agilent-enabled services to global research community
- Dynamic: Create new, privacy-protected online portal that Agilent customers can use to search and request a quote for Agilent-enabled research services directly from Agilent.com
- Science Exchange’s verification program used to qualify listed providers
- Partners to co-market new portal starting Feb.
|
Agilent |
University of Southern California Michelson Center for Convergent Bioscience |
- Objective: Create an Agilent Center of Excellence in Biomolecular Characterization
- Dynamic: Center will be place where scientists and engineers can work together on multidisciplinary approaches to improve healthcare through new drugs, diagnostics and medical devices
|
Ambry Genetics |
Invicro |
- Objective: Offer customized genomics and imaging services for biotechnology and pharmaceutical industry, with specialized focus on oncology and neurodegenerative diseases
- Dynamic: Combine Invicro’s imaging services and software with Ambry’s genomics services
- Both firms owned by Konica Minolta via latter’s 2017 acquisition of Ambry but operate as independent subsidiaries
|
Avalon GloboCare |
Da An Gene (China) |
- Objective: Accelerate exosome-based in vitro diagnostic product development and commercialization
- Dynamic: Strategic alliance combining Avalon’s exosome technology with Da An Gene’s proprietary core technology platform of fluorescent-quantitative PCR diagnostic reagents
|
Oxford Biodynamics |
Holos Life Sciences |
- Objective: Develop non-invasive epigenetic biomarkers linked to sports-related concussions
- Dynamic: Holos to supply participants’ blood samples and Oxford to provide its EpiSwitch epigenetic biomarkers development platform which partners will use to establish and monitor epigenetic changes and potential physiological reprogramming caused by a sports-related concussion
|
Access Bio |
Atomo Diagnostics |
- Objective: Provide point-of-care HIV testing in global markets
- Dynamic: Atomo to make its AtomoRapid lateral flow platform availabe for use with Access Bio rapid test detecting HIV antibodies from single drop of blood from a fingertip
|
Foundation Medicine |
European Organisation for Research and Treatment of Cancer (EORTC) |
- Objective: Provide cancer genomic profiling tests to determine patient eligibility for clinical trials
- Dynamic: Foundation Medicine to use its genomic profiling assays to provide testing services for EORTC’s Screening Patients for Efficient Clinical Trial Access (SPECTA) program
|
Biodesix |
Colorado Cancer Center |
- Objective: Develop a blood-based assay to identify non-small cell lung cancer patients likely to respond to certain immunotherapies
- Dynamic: CU Cancer Center research lab to analyze prospectively collected tissue samples with matched plasma from NSCLC patients
- Biodesix to use results in its development of test for PD-L1
|
SkylineDx |
Mayo Clinic |
- Objective: Develop diagnostic tests to improve clinical decision-making for melanoma patients
- Dynamic: Leverage Skyline’s informatics expertise to further optimize Mayo Clinic algorithm identifying risk factors for metastasis
|
Nebion |
Qlucore |
- Objective: Provide data analysis support for clinical research
- Dynamic: Deepening of collaboration began in 2014 allowing for combined use of Qlucore’s Omics Explorer and Nebion’s Genevestigator by scientists for data storage, pre-processing, analysis, interpretation and comparisons with public datasets, among other applications
|
PlexBio |
Denka |
- Objective: Accelerate detection of infectious disease and multidrug resistance
- Dynamic: Expand existing collaboration to include codevelopment of a molecular diagnostic platform for infectious disease testing
- New system to leverage PlexBio’s multiplex πCode MicroDisc technology and initially focus on tests for sepsis and multidrug resistance
|
Prometheus Research |
Stanford University |
- Objective: Create genetic registry as part of sleep medicine study
- Dynamic: Prometheus to join and collate highly disparate data from multiple sources in support of Stanford Technology Analytics and Genomics in Sleep (STAGES) study collecting and analyzing sleep data alongside biological samples from 30,000 patients
|
Tempus |
NYU School of Medicine |
- Objective: Develop personalized pancreatic cancer treatments
- Dynamic: Tempus to analyze data from roughly 500 pancreatic cancer patients and use NGS tests to generate additional genomic data to identify genetic patterns for use in predicting patient response to different therapies
- Recent academic collaborators of Tempus include Vanderbilt, Ohio Univ., Univ. of Penn. Abramson Cancer Center and Mayo Clinic
|
Biocartis |
Immunexpress |
- Objective: Develop Immunexpress’ Septicyte tests for use on Biocartis’ Idylla platform
- Dynamic: Tests based on biomarker signatures that gauge response of patient’s immune system to infections
- Immunexpress to lead commercialization, starting with US and Europe
|
UgenTec |
MDxHealth |
- Objective: Develop artificially intelligent software to support interpretation of molecular test results for MDxHealth’s ConfirmMDx and SelectMDx prostate cancer tests
- Dynamic: “This [automation step] will… also provide our SelectMDx IVD customers with an advanced software they can use [to] support and standardize drafting of result reports,” according to MDxHealth CEO
|
DISTRIBUTION, SALES & MARKETING AGREEMENTS |
Property Owner |
Distributor |
Deal Summary |
SenzaGen |
Eurofins BPT Munich |
- Products: SenzaGen’s GARD skin allergy tests
- Territory: Global
- Covers both GARDskin allergic contact dermatitis test, and GARDpotency add-on test subcategorizing sensitizing compounds as strong/moderate/non-sensitizing
|
OncoDNA |
NM Genomix |
- Products: OncoDNA’s tumor profiling products (specific products not disclosed)
- Territory: Bulgaria
|
OncoDNA |
Genext |
- Products: OncoDNA’s OncoDeep solid tumor test, OncoTrace and OncoSelect liquid biopsy tests, OncoStrat& Go solid and liquid biopsy combination, OncoKDM data interpretation and reporting software
- Territory: Russian Federation
|
BioPorto |
Roche |
- Product: BioPorto’s neutrophil gelatinase-associated lipocalin (NGAL) test for use on Cobas c 501 and Cobas c 502 analyzers
- Territory: Global
|
BioGx |
Launch Diagnostics |
- Products: Assays produced by BioGx’s European subsidiary
- Territories: UK, Ireland
|
BioGx |
AxonLab |
- Products: BioGx’s entire CE-IVD product line, plus laboratory-use-only products
- Territories: Austria, Belgium, Czech Republic, Germany, Slovenia, Switzerland, Croatia
|
Sysmex |
McKesson Medical- Surgical |
- Product: Sysmex’s new automated hematology analyzer
- Territory: Not disclosed
- Exclusive distribution deal
|
VHLGenetics |
PharmaDNA |
- Products: Genetic assays
- Territories: Estonia, Latvia, Lithuania
|
VHLGenetics |
Progènes |
- Products: Animal applications
- Territory: France
|
VHLGenetics |
Agrotis |
- Products: Genetic assays under Laboratory Genetics and Services brand name
- Territory: Italy
|
VHLGenetics |
Inno Laboratório Veterinário |
- Products: Cat and dog products
- Territory: Portugal
|
Amoy Diagnostics |
Medikonia |
- Products: Amoy Diagnostics’ molecular diagnostic tests
- Territories: Macau, Hong Kong
|
Technogenetics |
Immunodiagnostic Systems |
- Technogenetics’ automated assay kits for detecting and monitoring autoimmune and infectious diseases
- Territory: Global
- 10-year term
- Products to be sold under IDS brand
|
Lucigen |
GeneSuz Biochemical & Genetics |
- Products: Not specified
- Territory: Turkey
|
Lucigen |
Diagnostech |
- Products: Not specified
- Territory: South Africa
|
Lucigen |
Albiogen |
- Products: Not specified
- Territory: Russia
|
Lucigen |
Gene Target Solutions |
- Products: Not specified
- Territory: Australia
|
LICENSES |
Licensor |
Licensee |
Deal Summary |
Dynamic Combinatorial Chemistry |
DNA Script |
- Property: Novel DNA building block for use in enzymatic DNA synthesis
- Exclusive
|
University of California, San Francisco |
Vela Diagnostics |
- Property: Two methods for enriching rare sequences
- Vela to use the technologies to develop oncology and infectious disease tests, including for cell-free DNA and RNA testing and microbiology tests
|
SUPPLY, SERVICE & TESTING AGREEMENTS |
Supplier/Servicer |
Client |
Deal Summary |
Thermo Fisher Scientific |
OpGen |
- OpGen to use Thermo Fisher’s real-time PCR technology in its Acuitas AMR Gene Panel tests
|
Abbott |
Angle |
- Abbott to supply PathVysion HER-2 DNA FISH kits for Angle study investigating analysis of circulating tumor cells
- Aim of Angle study is to demonstrate that its Parsortix system can be used to harvest CTCs from blood of metastatic breast cancer patients
|
Illumina |
Harvard Pilgrim Health Care |
- Illumina to provide noninvasive prenatal testing to women with average-risk pregnancies
- Value-based contract under which Harvard Pilgrim will cover NIPT for average-risk pregnancies and Illumina will reimburse Harvard Pilgrim if one-year costs of testing exceed pre-established baseline
|
Exosome Diagnostics |
FedMed |
- Exosome Diagnostics to provide its ExoDx Prostate test via FedMed, a US PPO with 40 million members as a covered benefit
|