MERGERS & ACQUISITIONS |
Acquiring Company |
Target(s) |
Deal Summary |
Siemens |
Alere’s Epocal point-ofcare blood diagnostic unit |
- Price: Undisclosed
- Status: To close by end of Sept.
- Sale contingent on consummation of Abbott Alere merger
|
Quidel |
Alere’s triage MeterPro cardiovascular and toxicology assets and B-type Naturietic Peptide (BNP) assay business |
- Price: $400 million + $40 million in contingent payments paid as mix of cash and loans
- Status: To close by end of Sept.
- Sale contingent on consummation of Abbott Alere merger
|
Roche |
mySugr |
- Price: Undisclosed
- Status: Closed
- Privately held mySugr produces a mobile devices logbook to help people track their blood sugar, medications and activity levels
|
Konica Minolta |
Ambry Genetics |
- Price: Up to $1 billion cash, including $800 million upfront and up to $200 million over 3 years
- Status: Expected to close in 3Q
- Ambry to become subsidiary of Konica Minolta and keep its name and continue its genetic testing operation from its current California HQ
|
Thermo Fisher Scientific |
Linkage Biosciences |
- Price: Undisclosed
- Status: Closed
- SF-based Linkage, known for its LinkSeq product line, becomes part of Thermo Fisher’s One Lambda transplant Dx business
|
Quest Diagnostics |
Laboratory businesses Med Fusion and Clear Point in Lewisville, Texas |
- Price: Undisclosed
- Status: Closing of previously announced deal
- Quest acquires business’ 200,000 sq. foot facility and becomes a preferred provider to several organizations that are former owners of one or both businesses
|
Quest Diagnostics |
Outreach laboratory services business of Cape Cod Healthcare |
- Price: Undisclosed
- Status: Non-binding letter of intent subject to negotiation of terms and regulatory approval, which is expected to occur by Jan. 1, 2018
- Deal comes on heals of Quest’s acquisition of PeaceHealth Laboratories’ outreach lab services operations
|
SOL Group |
Personal Genomics |
- Price: Undisclosed
- Status: Italy-based SOL acquires 51% stake
- SOL to finance expansion of PG’s tests for genetic disorders and early cancer diagnosis
|
Eurofins |
Genoma Laboratory Group |
- Price: Undisclosed
- Status: Expected to close in July
- Eurofins gains entry to Italian testing market and strengthens its position in specialty diagnostics across Europe
- Deal follows Eurofins’ acquisition of GATC Biotech, which is also expected to close in July
|
Philips |
Spectranetics Corp |
- Price: €1.9 billion ($2.16 billion) + debt
- Acquisition of Spectranetics’ guidance tech for heart disease expands Philips’ image-guided therapy line
- Deal not expected to increase Philips’ return on invested capital for 5 years
|
Philips N.V. |
Electrical Geodesics Inc. |
- Price: Purchase price based on £29 million ($36.7 million) valuation of EGI
- Status: Expected to close in 3Q
- Philips drawn by EGI’s EEG platform technology, which gathers brain-activity data from many more electrodes than conventional EEG products
|
PerkinElmer |
Euroimmun Medical Laboratory Diagnostics (based in Germany) |
- Price: Approximately $1.3 billion cash
- Status: Expected to close in 4Q
- Acquisition of Euroimmun, recognized as a global leader in autoimmune testing and emerging force in infectious disease and allergy testing, expands PerkinElmer’s reach into autoimmune and allergy diagnostic markets, and enables it to offer “new infectious disease capabilities to customers in China,” according to a company spokesman
|
Invitae |
Ommdom (health software developer) |
- Price: Roughly $6 million in Invitae common shares in exchange for all Ommdom outstanding capital stock
- Status: Closed
- Acquisition of Ommdom’s CancerGene Connect platform for collecting and managing genetic family histories expands its existing suite of technologies for using genetic information in mainstream medical care
|
STRATEGIC ALLIANCES, PARTNERSHIPS & COLLABORATIONS |
Partner 1 |
Partner 2 |
Deal Summary |
Asia Genomics |
CellMax Life |
- Objective: Make CellMax’s cancer tests available throughout Southeast Asia
- Dynamic: Partnership in which Asia Genomics will make tests available immediately through hospitals and clinics in region, and directly to consumers “where appropriate”
|
Trovagene |
Novogene (Chinese genomics service provider) |
- Objective: Develop tests for Chinese market
- Dynamic: Novogene to validate Trovagene’s Next Collect urine collection and nucleic acid preservation device, which is currently approved for research only, for commercial use in China
|
Nestle Health Science |
Enterome |
- Objective: Develop microbiome diagnostics for inflammatory bowel disease, liver disorders and other indications
- Dynamic: 50/50 joint venture forming startup company called Microbiome Diagnostics Partners
|
Biocartis |
Exploit Technologies |
- Objective: Develop molecular breast cancer and other tests to be run on Biocartis’ PCR-based Idylla platform
- Dynamic: 5-year alliance
- Biocartis responsible for commercializing tests under its own label
- ETPL to act as a development partner via Singapore’s Diagnostics Development Hub
|
Counsyl |
Angsana Molecular & Diagnostics Laboratory |
- Objective: Commercialize Counsyl’s expanded carrier screening test in Hong Kong
- Dynamic: Samples to be processed at Counsyl’s CLIA-certified San Francisco lab
|
Bionano Genomics |
Genoptix |
- Objective: Co-develop diagnostic assays for hematologic oncology indications
- Dynamic: Exclusive deal combining Bionano’s Saphyr system for visualizing the structure of a genome and Genoptix’s expertise in hematology and oncology
|
Rennova Health |
Certainty Health |
- Objective: Develop smartphone-based platform for offering molecular tests for precision treatment of psychiatric disorders
- Dynamic: Rennova to offer genetic tests developed by its Advanced Molecular Services Group subsidiary directly to consumers via mobile platform
|
Quest Diagnostics |
Wal-Mart Stores |
- Partnership to bring Quest’s laboratory testing services to 15 Walmart locations in Florida and Texas by end of 2017
|
Adaptive Biotechnologies |
Janssen Pharmaceuticals |
- Objective: Study clinical effectiveness of Jannsen’s Darzalex drug for treating multiple myeloma (MM)
- Dynamic: Adaptive will use its NGS-based ClonoSeq assay to measure minimal residual disease in MM patients treated with Darzalex in clinical trials
|
BGI |
University of Debrecen in Hungary |
- Partnership to establish a next-generation sequencing laboratory and collaborate on genomics research projects
|
MDxHealth |
QUT bluebox (commercialization arm of Queensland University of Technology) |
- Objective: Develop liquid biopsy epigenetic assay for early detection of oral cancer
- Dynamic: MDxHealth to have first option to license the commercial diagnostic rights
- Proceeds to support firm’s urologic cancer diagnostics R&D platform as well as University research activities
|
Thermo Fisher Scientific |
OpGen |
- Objective: Commercialize OpGen’s Acuitas molecular products and informatics system for fighting multidrug-resistant infections
- Dynamic: OpGen to combine its Acuitas Rapid Test for Pathogen ID with Thermo Fisher’s real-time PCR solutions
|
Human Longevity |
Merck KGaA |
- Objective: Identify treatment-response biomarker signatures in advanced melanoma patients
- Dynamic: HL to generate and analyze genomic sequencing data from clinical trial participants’ tumors and germline DNA
|
EntroGen |
University of Southern California Norris Comprehensive Cancer Center |
- Collaboration to evaluate clinical utility of EntroGen’s liquid biopsy real-time PCR test in lung cancer patients
|
FlowJo |
Becton Dickinson |
- Objective: Co-marketing
- Dynamic: Companies to market FlowJo Envoy cloud-based data-analysis software with BD’s FACSymphony a cell analyzer for simultaneous measurement of up to 50 characteristics of a single cell
|
FlowJo |
Cytapex Bioinformatics |
- Partnership to provide bioinformatics consulting and services in flow cytometry data analysis using the FlowJo application
|
Siemens Healthineers |
Fast-track Diagnostics |
- Objective: Expansion of Siemens’s molecular testing product line
- Dynamic: Siemens to add a range of Fast Track’s CE-marked kits and multi-syndromic panels to its own Versant kPCR Molecular System menu
- Jackson scientists to form genomics research collaborations with WMU investigators in US and China
|
LifeLabs |
GenXys Health Care Systems |
- Objective: Offer pharmacogenetic testing services in Canada
- Dynamic: LifeLabs to analyze patient cheek swab samples to look for 60 genetic variations that can affect drug metabolism and response
- Results to be added to GenXys’ TreatGxPlus software
|
Trovagene |
AstraZeneca |
- Objective: Evaluate whether blood and urine testing in combination is as effective as tissue testing in identifying epidermal growth factor receptor T790M mutation status
- Dynamic: AstraZeneca to use Trovagene’s Trovera EGFR urine liquid biopsy test to conduct biomarker study
|
HTG Molecular Diagnostics |
Qiagen |
- Objective: Develop sequencing-based companion diagnostic assay
- Dynamic: Qiagen to pay low single digit millions of dollars for initial phase development work performed by HTG and share in net profits generated by initial phase
|
CloudHealth Genomics (based in Shanghai) |
Mongolian Health Initiative |
- Collaboration to advance precision medicine research for nutritional deficiencies and nutrition-related diseases
|
Tempus |
University of Michigan’s Comprehensive Cancer Center |
- Objective: Use molecular data to identify most effective care for breast cancer
- Dynamic: Tempus to use bioinformatics and machine learning to analyze molecular, phenotypic, therapeutic and outcome data from UM patients
- Tempus has similar collaborations with University of Chicago, Duke, University of Pennsylvania, Ohio’s University Hospitals Seidman Cancer Center and Mayo Clinic
|
GeneDx (owned by Opko Health) |
University of California |
- Objective: Track physician utilization of genetic tests
- Dynamic: Expansion of current agreement to cover more than 400 tests for rare hereditary disorders
|
DISTRIBUTION, SALES & MARKETING AGREEMENTS |
Property Owner |
Distributor |
Deal Summary |
Molecular Biology Systems (MBS) |
Isogen Life Sciences |
- Product: MBS’s NextGen PCR thermal cycler
- Territories: Belgium, Netherlands, Luxembourg and Spain
- Exclusive
|
OneOme |
Total Quality Medicine (TQM) |
- Products: OneOme’s PCR-based RightMed genetic test to be incorporated into TQM’s GeneTest line of personalized medicine products
- Territory: Mexico
|
Dovetail Genomics |
Tree Code |
- Products: Dovetail’s genome assembly services
- Territories: Singapore, Malaysia, Thailand, Vietnam, Indonesia, Philippines and Myanmar
|
OncoDNA |
Shchurko |
- Products: OncoDeep solid tumor test, OncoTrace and OncoSelect liquid biopsy tests, OncoStrat&Go and OncoKDM data reporting software
- Territory: Belarus
|
Streck |
Golden Bat Far East |
- Products: Streck’s cell stabilization, molecular and core products
- Territory: Philippines
|
MDxHealth |
IPS Genomix |
- Product: SelectMDx for Prostate Cancer test
- Territories: Lebanon, Egypt, United Arab Emirates, Saudi Arabia, Oman, Bahrain, Qatar and Jordan
|
GenePOC |
Cardinal Health |
- Products: GenePOC’s revogene instrument and associated assays
- Territory: US
- Exclusive
|
OncoDNA |
Zogen |
- Products: OncoDNA products for molecular profiling of liquid biopsies and solid tumor tissue for personalized medicine
- Territory: Mexico
|
Canopy Biosciences |
Cosmo Bio |
- Products: Canopy’s genetic engineering products
- Territory: Japan
|
Genomic Vision |
APG Bio |
- Products: Genomic Vision’s products and services to be offered to life science researchers
- Territories: China, Hong Kong and Macau
|
GenePeeks |
Alliance Global Group |
- Products: GenePeeks’ Preconception Screen
- Territories: Middle East and Africa
|
Cynvenio Biosystems |
Bio-Medical Science |
- Products: Cynvenio’s ClearID line of liquid biopsy tests
- Territory: South Korea
|
Cynvenio Biosystems |
ProgeniTest |
- Products: Cynvenio’s ClearID line of liquid biopsy tests
- Territory: Argentina
|
Cynvenio Biosystems |
Karyo |
- Products: Cynvenio’s ClearID line of liquid biopsy tests
- Territory: Greece
|
Cynvenio Biosystems |
Pronto Diagnostics |
- Products: Cynvenio’s ClearID line of liquid biopsy tests
- Territory: Israel
|
Biodesix |
Positive Bioscience |
- Products: Biodesix’s GeneStrat and VeriStrat
- Territory: India
- All testing to be done at Biodesix’s Boulder, Colorado lab
|
SpeeDx (Australia) |
Cepheid |
- Products: SpeeDx’s PlexPCR and ResistancePlus multiplex real-time PCR products
- Territories: UK, Germany, France and Italy
- Expansion of current deal allowing Wallac to distribute Amplidiag in South Africa
|
LICENSES |
Licensor |
Licensee |
Deal Summary |
SISCAPA Assay Technologies |
Waters |
- Property: Stable isotope-labeled standards technology to be used by Waters for standardizing quantitative mass spec assays
- Territory: Undisclosed
- Non-exclusive
|
Inventors from Max Delbrück Center for Molecular Medicine, Genetic Information Research Institute and Paul Ehrlich Institute |
Horizon Discovery |
- Property: Transposon-based gene-editing technology
- Territory: Undisclosed
- Exclusive
|
SUPPLY, SERVICE & TESTING AGREEMENTS |
Supplier |
Client |
Deal Summary |
GenomOncology |
University of California, San Francisco |
- UCSF to use GenomOncology’s informatics platform to analyze and report results from its UCSF500 NGS cancer panel
|
Illumina |
Genomics England |
- GE to use Illumina’s BaseSpace Variant Interpreter for tumor and matched normal samples characterized as part of 100,000 Genomes Project
|
Personal Genome Diagnostics said today that it will now |
US Department of Veterans Affairs |
- PGD to provide its PlasmaSelect 64 liquid biopsy test to advanced cancer patients being treated at VA facilities
|