STRATEGIC ALLIANCES, PARTNERSHIPS & COLLABORATIONS |
Partner 1 |
Partner(s) 2+ |
Deal Summary |
3M |
Massachusetts Institute of Technology |
- Objective: Developing rapid antigen test for SARS-CoV-2
- Dynamic: Viral antigen test would provide test results within minutes using a paper-based device at the point of care and be scaled to produce millions of units per day
|
Centogene |
Molecular Health |
- Objective: Develop new orphan drugs, starting with epilepsy
- Dynamic: Carry out project called Real-life data and Innovative Bioinformatic Algorithms (RIBA) combining Centogene’s real-life data sets in rare diseases with Molecular Health’s expertise in big data, AI and computational algorithms
|
MP Biomedicals Asia Pacific |
Singapore’s Agency for Science, Technology and Research (A*STAR) |
- Objective: Develop point-of-care antibody test for SARS-CoV-2
- Dynamic: Test has provisional regulatory authorization in Singapore regulators and is being distributed in Europe, Africa and South America with plans to seek EUA from FDA
|
Ultivue |
OracleBio |
- Objective: Offer pharmaceutical companies end-to-end workflow for tissue-based biomarker analysis
- Dynamic: Firms to combine respective technologies for tissue staining and histopathology image analysis
|
BostonGene |
NEC |
- Objective: Analyze molecular profiles and tumor microenvironments of cancer patients in NEC’s clinical trials to improve cancer treatment response
- Dynamic: BostonGene to perform integrated genomic and transcriptomic next-generation sequencing on tumors of select patients across different cancer types and disease stages and analyze tumor microenvironment activity
|
Saga Diagnostics |
SensID |
- Objective: Develop control reagents for cancer mutation detection
- Dynamic: Use use SensID’s controls with Saga’s digital PCR-based Sagasafe technology for detecting and quantifying ctDNA in cancer patients at ultra-low allelic frequencies
|
Microba |
Synlab |
- Objective: Launch MyBiome gut microbiome test in Europe and Latin America
- Dynamic: Test measures bacterial species in gut microbiome and calculates their metabolic potential in relation to healthy reference ranges
|
Helix |
San Diego County (California) |
- Objective: Provide COVID-19 molecular diagnostics tests
- Dynamic: Provide up to 2,000 of Helix’s RT-qPCR assays per day out of Helix’s San Diego lab
|
Thermo Fisher Scientific |
First Genetics |
- Objective: Commercialize NGS-based diagnostics in Russia
- Dynamic: First Genetics, a Russian manufacturer, to market its IVD assays and F-Genetics NGS System, which is based on Thermo Fisher’s Ion GeneStudio S5 sequencer, to Russian labs for reproductive health and cancer testing
|
Thermo Fisher Scientific |
Chugai Pharmaceutical (part of Roche group) |
- Objective: Develop CDx to identify ROS1-positive non-small cell lung cancer patients who may be eligible for treatment with entrectinib (Genentech’s Rozlytrek, marketed in Japan by Chugai)
- Dynamic: Thermo Fisher to also seek Ministry of Health, Labor, and Welfare of Japan approval to expand use of Oncomine Dx Target test in Japan
|
Twist Bioscience |
Takeda Pharmaceutical Company |
- Objective: Develop new antibodies for oncology, rare disease, neuroscience and gastroenterology therapies
- Dynamic: Twist to give Takeda access to its phage display libraries for use in discovery, validation and optimization of antibodies needed to develop new biologics in exchange for annual technology licensing fees, milestones and royalties for all compounds discovered from Twist libraries
|
Smiths Detection |
Attomarker |
- Objective: Develop and manufacture SARS-CoV-2 antibody testing device
- Dynamic: Create miniaturized version of Attomaker Triple Antibody Test that works with smartphones to enable point-of-care and at-home testing
|
Guardant Health |
Janssen Biotech |
- Objective: Seek regulatory approval for and commercialize Guardant360 assay as CDx for amivantamab, Janssen’s investigational EGFR-MET bispecific antibody for treating non-small cell lung cancer
- Dynamic: Agreement covers US, Canada, Japan and Europe
|
Myriad Genetics |
OptraHealth |
- Objective: Develop chatbot named Gene to offer patients hereditary cancer information
- Dynamic: Gene to fuse OptraHealth’s GeneFax AI platform with Myriad’s online hereditary cancer quiz
|
Genomics England |
Amazon Web Services
+
Lifebit |
- Objective: Create platform for researching COVID-19 data and analytics
- Dynamic: Include data from Genomics England’s research partnership with the Genetics of Mortality in Critical Care (GenOMICC) consortium, the NHS, and Illumina to sequence genomes from up to 35,000 SARS-CoV-2 patients
|
Proscia |
Royal Philips |
- Objective: “Advance an open ecosystem” to accelerate and scale adoption of digital pathology by labs
- Dynamic: Integrate Philips’ image format with Proscia’s digital pathology platform
|
Pressure Biosciences (PBI) |
Leica Microsystems (part of Danaher) |
- Objective: Globally comarket mass spectrometry sample preparation platform
- Dynamic: Platform combines Leica’s laser microdissection (LMD) technology for precise cutting of small biopsy samples, and PBI’s pressure cycling technology (PCT), for protein extraction and digestion from samples for mass spec analysis
|
Burning Rock Biotech |
CStone Pharmaceuticals |
- Objective: Co-develop and commercialize companion diagnostics for Blueprint Medicines’ pralsetinib in China
- Dynamic: Firms to promote standardization of RET gene testing in China
|
DISTRIBUTION, SALES & MARKETING AGREEMENTS |
Property Owner |
Distributor |
Deal Summary |
Oncocyte |
ProGenetics |
- Products: Oncocyte’s DetermaRx test to identify patients at high risk for lung cancer recurrence who may benefit from adjuvant chemotherapy after tumor removal surgery
- Territory: Israel
|
Menarini Silicon Biosystems |
OpGen |
- Products: Menarini’s Cellsearch Circulating Endothelial Cell (CEC) Kit
- Territory: North America
|
3D Medicines |
Todos Medical |
- Products: 3D Medicines’ qPCR test kits and SARS-CoV-2 test
- Territory: US
- Todos gets exclusive right to seek FDA Emergency Use Authorization for test
|
LICENSES |
Licensor |
Licensee |
Deal Summary |
Massachusetts Institute of Technology |
PathSensors |
- Expands current exclusive license to CANARY pathogen detection technology to include clinical applications starting with SARS-CoV-2
|
Massachusetts General Hospital |
ProterixBio |
- ProterixBio licenses ELISA-based serology test measuring antibodies that bind to receptor binding domain of SARS-CoV-2 spike protein
|
NEW CLINICAL STUDIES |
DX Partner |
Other Partner(s) |
Description of Study |
BioReference Laboratories (Opko Health subsidiary) |
US Centers for Disease Control and Prevention |
- Indefinite Delivery Indefinite Quantity (IDIQ) contract to provide antibody testing for national SARS-CoV-2serological survey
|
Quidel |
US Department of Health and Human Services |
- HHS to purchase 2,000 Sofia and Sofia 2 instruments and 750,000 Sofia SARS Antigen FIA tests to detect SARS-CoV-2 in nursing homes
|