Partner 1 |
Partner(s) 2+
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Deal Summary
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Single Cell Discoveries |
BioTuring |
- Objective: Integrate firms’ respective single-cell sequencing products
- Dynamic: Single Cell Discoveries to offer BioTuring’s BBrowser single-cell multiomics analysis platform as part of its single-cell sequencing services
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Thermo Fisher Scientific |
Oncocyte |
- Objective: Clinically validate Thermo Fisher's Oncomine Comprehensive Assay Plus and develop Oncocyte’s DetermaIO assay on Ion Torrent Genexus system
- Dynamic: Under comarketing agreement running through 2035, Thermo subsidiary Life Technologies to retain exclusive right to partner with pharma companies to develop its Oncomine test as a companion diagnostic, HealthPulse@home into lab systems using LumiraDx’s SARS-CoV-2 RNA Star Complete test
- Oncocyte keeps exclusive right to partner with therapeutics companies to develop DetermaIO as a companion diagnostic
- Thermo Fisher to pay Oncocyte a low- to mid-20s percentage of revenue it receives on worldwide sales of a resulting Oncomine IVD test and on sales of DetermaIO IVD outside US
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Illumina |
Agendia |
- Objective: Develop IVD tests for oncology testing
- Dynamic: Multi-year collaboration to leverage the Illumina MiSeqDx sequencing platform to create new diagnostics to improve breast patient cancer care and management
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Illumina |
SomaLogic |
- Objective: Create multiplexed, high-throughput proteomics assays with NGS-based readout
- Dynamic: Codevelopment agreement with Illumina to develop and market protein detection assays based on SomaLogic's SomaScan platform that run on Illumina's high-throughput NGS platforms, including NovaSeq
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Illumina |
Syapse |
- Objective: Assess uptake and actionability of comprehensive genomic profiling in community oncology health system setting
- Dynamic: Do study using data from Syapse Learning Health Network data aggregation platform to identify trends in testing approaches over time and actionability of results
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Scienion |
Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA) |
- Objective: Develop multiplexed, lateral-flow diagnostic platform for bladder cancer
- Dynamic: Leverage IPA’s knowledge of biomarkers and biobank 500 urine samples to create test and Scienon’s automated precision dispensing technology to print biomarkers on the lateral flow immunoassay
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Yourgene |
EKF Diagnostics |
- Objective: Offer noninvasive prenatal and other genomic testing services in US
- Dynamic: 5-year deal with Yourgene to provide EKF subsidiary and CLIA lab Advanced Diagnostics Laboratory with proprietary reagents and NGS analysis software for use in creating noninvasive prenatal testing service providing results within 48 hours
- ADL to also offer Yourgene's PCR tests for cystic fibrosis, aneuploidy, and DPYD deficiency in chemotherapy toxicity
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Veranome |
Cold Spring Harbor Laboratories (CSHL) |
- Objective: Develop new applications using CSHL's BARseq platform
- Dynamic: Collaboration and licensing agreement bringing CSHL’s in situ sequencing and data analytics technologies into Veranome's spatial omics portfolio
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Cardea Bio |
Siemens Healthineers Center for Innovation in Diagnostics |
- Objective: Assess feasibility of developing biosensor testing applications for Cardea's BPU Platform
- Dynamic: Optimize and test a next-generation SARS-CoV-2 immunoassay
- Hardware, software, wetware, and know-how to be transferred to Siemens Healthineers' facilities to enable use of and experimentation with BPU Platform
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Becton Dickinson |
Pfizer + Wellcome (charitable foundation) |
- Objective: Study the role of diagnostics in supporting antimicrobial stewardship practices
- Dynamic: Survey existing diagnostic practices to understand the benefits and gaps in diagnostic testing in antimicrobial resistance stewardships
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Caris Life Sciences |
HotSpot Therapeutics |
- Objective: Develop HotSpot's precision medicine products and potential companion diagnostic tests
- Dynamic: Strategic collaboration to initially focus on therapeutic programs using HotSpot's E3 ubiquitin ligase immunotherapy program from pre-first-in-human trials to potential CDx tests and product launch
- Caris has negotiation rights for CDx tests resulting from partnership
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NeoGenomics |
Biomarker Collaborative |
- Objective: Expand cancer patient access to biomarkers testing
- Dynamic: Biomarker to prepare resource page to be provided to patients whose lung cancer biomarker is identified with NeoGenomics' tests
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Grail |
PINC AI |
- Objective: Identify patients who may benefit from early cancer detection using Galleri, Grail's multi-cancer early detection blood test
- Dynamic: PINC AI plans to augment its artificial intelligence-enabled clinical decision support platform to alert doctors to patients with higher risks of cancer who may benefit from early testing using Galleri
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C2i Genomics |
OncoDNA |
- Objective: Pair C2i's AI-based whole-genome sequencing and minimal residual disease cancer monitoring platform with OncoDNA's European network of cancer clinician-researchers
- Dynamic: Support interventional clinical trial led by Paris' Gustave Roussy Institute to test the clinical utility of escalating metastatic treatments in over 750 patients with high risk of cancer recurrence
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Exagen |
Queen Mary University of London |
- Objective: Develop patented molecular signatures for rheumatoid arthritis therapy selection
- Dynamic: Exagen gets exclusive global license from Queen Mary University to patent-pending tests that use RNA expression patterns to predict patient response to commonly prescribed therapeutics for rheumatoid arthritis
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Acon Laboratories |
AusDiagnostics |
- Objective: Launch Acon’s over-the-counter Flowflex COVID-19 Home Test in Australia
- Dynamic: Acon's Flowflex test is a lateral flow assay to detect SARS-CoV-2 nucleocapsid protein antigen in self-collected anterior nasal swab specimens
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Qiagen |
Actome |
- Objective: Develop protein analysis applications for the QIAcuity digital PCR system
- Dynamic: Comarketing agreement giving Qiagen a co-exclusive license for digital PCR applications to use Actome's patented protein-interaction-coupling (PICO)-technology on QIAcuity
- Qiagen also makes undisclosed investment in German startup
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Singular Genomics Systems |
Broad Institute |
- Objective: Connect Singular’s G4 next-generation sequencing platform to the Terra data platform
- Dynamic: Partnership giving researchers who use the Singular G4 access to cloud-based data storage and analytical tools optimized for genomic data
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Twist Bioscience |
Artisan Development Labs (Artisan Bio) |
- Objective: Discover new antibodies against 5 undisclosed targets
- Dynamic: Apply Twist’s Library of Libraries to discover novel antibodies directed against Artisan Bio's immunotherapy targets, and leverage Artisan’s Immune Cell Engineering Foundry and STAR Guides to develop custom cell therapeutics
- Twist to receive upfront technology access and project fees for each program, milestone payments and royalties on product sales
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Bio-Techne |
Akoya Biosciences |
- Objective: Develop a single-cell, spatial multiomics workflow for analysis of tissue samples
- Dynamic: Combine Akoya’s PhenoCycler-Fusion workflow with Bio-Techne’s RNAScope HiPlex v2 assay
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Pacific Biosciences |
Care4Rare Canada Consortium |
- Objective: Study complex cases of rare disease with whole-genome sequencing
- Dynamic: Use PacBio's HiFi long-read sequencing technology to study rare disease samples that have been sequenced with short-read technology, but for which no causative genetic variants were identified
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Alamar Biosciences |
Abcam |
- Objective: Further proteomics research
- Dynamic: Combine Alamar's NUcleic acid-Linked Immuno-Sandwich Assay (NULISA) proteomics platform and Abcam's antibody portfolio
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Mission Bio |
SequMed |
- Objective: Create new single-cell assays for early cancer detection
- Dynamic: Combine Mission Bio's Tapestri platform with SequMed's clinical assay development and data analysis capabilities
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