New Colorectal Cancer Screening Guidelines Are a Windfall for Exact Sciences, Cologuard
If you held stock in Exact Sciences on May 17, chances are you went to bed happy on May 18. It was on May 18 that a U.S. government taskforce officially announced a change in its guidelines for colorectal cancer testing by recommending that screening begin at age 45, rather than 50. In addition to saving thousands of lives by promoting earlier detection, the announcement lifted the stock price of Exact Sciences, maker of Cologuard, the top selling molecular colorectal cancer screening tests that the task force recommends. The prospect of more users at an earlier age is certainly exciting news, especially since those late 40-somethings with commercial insurance won’t have to lay out any of their own money for Cologuard. The Diagnostic Challenge The New Colorectal Screening Recommendations The U.S. Preventive Services Task Force (USPSTF) reviews its screening recommendations every four years. The new recommendations, which were published in the Journal of the American Medical Association on May 18, are an update to its previous 2016 guidelines and a final version of draft recommendations published in October 2020. Colorectal cancer is the third leading cause of cancer death among adults in the U.S., with more than 52,000 people projected […]
Ages | Recommendations | Grade |
50 to 75 | Screening for all members | A |
45 to 49 | Screening for all members | B |
76 to 85 | Screening for selective cases determined by clinician based on patient’s health, screening history and preferences | C |
Stool-Based Tests | |
Test Type | Recommended Frequency |
High-sensitivity gFOBT | Every year |
FIT | Every year |
mtDNA | Every 1 to 3 years based on manufacturer’s recommendations |
Direct Visualization Tests | |
Test Type | Recommended Frequency |
Colonoscopy | Every 10 years |
CT colonography | Every 5 years |
Flexible sigmoidoscopy | Every 5 years |
Flexible sigmoidoscopy with FIT | Every 10 years + FIT every year |
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